what can i do with a phd in research

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9 things you should consider before embarking on a PhD

June 23, 2021 | 15 min read

By Andy Greenspon

The ideal research program you envision is not what it appears to be

Editor's Note:  When Andy Greenspon wrote this article, he was a first-year student in Applied Physics at Harvard. Now he has completed his PhD. — Alison Bert, June 23, 2021

If you are planning to apply for a PhD program, you're probably getting advice from dozens of students, professors, administrators your parents and the Internet. Sometimes it's hard to know which advice to focus on and what will make the biggest difference in the long-run. So before you go back to daydreaming about the day you accept that Nobel Prize, here are nine things you should give serious thought to. One or more of these tips may save you from anguish and help you make better decisions as you embark on that path to a PhD.

1. Actively seek out information about PhD programs.

Depending on your undergraduate institution, there may be more or less support to guide you in selecting a PhD program – but there is generally much less than when you applied to college.

On the website of my physics department, I found a page written by one of my professors, which listed graduate school options in physics and engineering along with resources to consult. As far as I know, my career center did not send out much information about PhD programs. Only after applying to programs did I find out that my undergraduate website had a link providing general information applicable to most PhD programs. This is the kind of information that is available all over the Internet.

So don't wait for your career center or department to lay out a plan for you. Actively seek it out from your career center counselors, your professors, the Internet — and especially from alumni from your department who are in or graduated from your desired PhD program. First-hand experiences will almost always trump the knowledge you get second-hand.

2. A PhD program is not simply a continuation of your undergraduate program.

Many students don't internalize this idea until they have jumped head-first into a PhD program. The goal is not to complete an assigned set of courses as in an undergraduate program, but to develop significant and original research in your area of expertise. You will have required courses to take, especially if you do not have a master's degree yet, but these are designed merely to compliment your research and provide a broad and deep knowledge base to support you in your research endeavors.

At the end of your PhD program, you will be judged on your research, not on how well you did in your courses. Grades are not critical as long as you maintain the minimum GPA requirement, and you should not spend too much time on courses at the expense of research projects. Graduate courses tend to be designed to allow you to take away what you will find useful to your research more than to drill a rigid set of facts and techniques into your brain.

3. Take a break between your undergraduate education and a PhD program.

You are beginning your senior year of college, and your classmates are asking you if you are applying to graduate school. You think to yourself, "Well, I like studying this topic and the associated research, and I am going to need a PhD if I want to be a professor or do independent research, so I might as well get it done as soon as possible." But are you certain about the type of research you want to do? Do you know where you want to live for the next five years? Are you prepared to stay in an academic environment for nine years straight?

Many people burn out or end up trudging through their PhD program without a thought about what lies outside of or beyond it. A break of a year or two or even more may be necessary to gain perspective. If all you know is an academic environment, how can you compare it to anything else? Many people take a job for five or more years before going back to get their PhD. It is true though that the longer you stay out of school, the harder it is to go back to an academic environment with lower pay and a lack of set work hours. A one-year break will give you six months or so after graduation before PhD applications are due. A two-year gap might be ideal to provide time to identify your priorities in life and explore different areas of research without having school work or a thesis competing for your attention.

Getting research experience outside of a degree program can help focus your interests and give you a leg up on the competition when you finally decide to apply. It can also help you determine whether you will enjoy full-time research or if you might prefer an alternative career path that still incorporates science, for example, in policy, consulting or business — or a hybrid research job that combines scientific and non-scientific skills.

I will be forever grateful that I chose to do research in a non-academic environment for a year between my undergraduate and PhD programs. It gave me the chance to get a feel for doing nothing but research for a full year. Working at the Johns Hopkins University Applied Physics Laboratory in the Space Division, I was the manager of an optics lab, performing spectroscopic experiments on rocks and minerals placed in a vacuum chamber. While my boss determined the overall experimental design, I was able to make my own suggestions for experiments and use my own discretion in how to perform them. I presented this research at two national conferences as well — a first for me. I was also able to learn about other research being performed there, determine which projects excited me the most, and thus narrow down my criteria for a PhD program.

4. Your current area of study does not dictate what you have to study in graduate school.

You might be studying the function and regulation of membrane proteins or doing a computational analysis of the conductivity of different battery designs, but that doesn't mean your PhD project must revolve around similar projects. The transition between college or another research job to a PhD program is one of the main transitions in your life when it is perfectly acceptable to completely change research areas.

If you are doing computation, you may want to switch to lab-based work or vice versa. If you are working in biology but have always had an interest in photonics research, now is the time to try it out. You may find that you love the alternative research and devote your PhD to it, you might hate it and fall back on your previous area of study — or you may even discover a unique topic that incorporates both subjects.

One of the best aspects of the PhD program is that you can make the research your own. Remember, the answer to the question "Why are you doing this research?" should not be "Well, because it's what I've been working on for the past few years already."While my undergraduate research was in atomic physics, I easily transitioned into applied physics and materials science for my PhD program and was able to apply much of what I learned as an undergraduate to my current research. If you are moving from the sciences to a non-STEM field such as social sciences or humanities, this advice can still apply, though the transition is a bit more difficult and more of a permanent commitment.

5. Make sure the PhD program has a variety of research options, and learn about as many research groups as possible in your first year.

Even if you believe you are committed to one research area, you may find that five years of such work is not quite what you expected. As such, you should find a PhD program where the professors are not all working in the same narrowly focused research area. Make sure there are at least three professors working on an array of topics you could imagine yourself working on.

In many graduate programs, you are supposed to pick a research advisor before even starting. But such arrangements often do not work out, and you may be seeking a new advisor before you know it. That's why many programs give students one or two semesters to explore different research areas before choosing a permanent research advisor.

In your first year, you should explore the research of a diverse set of groups. After touring their labs, talking to the students, or sitting in on group meetings, you may find that this group is the right one for you.

In addition, consider the importance of who your research advisor will be. This will be the person you interact with regularly for five straight years and who will have a crucial influence on your research. Do you like their advising style? Does their personality mesh with yours? Can you get along? Of course, the research your advisor works on is critical, but if you have large disagreements at every meeting or do not get helpful advice on how to proceed with your research, you may not be able to succeed. At the very least, you must be able to handle your advisor's management of the lab and advising style if you are going to be productive in your work. The Harvard program I enrolled in has professors working on research spanning from nanophotonics to energy materials and biophysics, covering my wide range of interests. By spending time in labs and offices informally chatting with graduate students, I found an advisor whose personality and research interests meshed very well with me. Their genuine enthusiasm for this advisor and their excitement when talking about their research was the best input I could have received.

6. Location is more important than you think — but name recognition is not.

The first consideration in choosing a PhD program should be, "Is there research at this university that I am passionate about?" After all, you will have to study this topic in detail for four or more years. But when considering the location of a university, your first thought should not be, "I'm going to be in the lab all the time, so what does it matter if I'm by the beach, in a city, or in the middle of nowhere." Contrary to popular belief, you will have a life outside of the lab, and you will have to be able to live with it for four or more years. Unlike when you were an undergraduate, your social and extracurricular life will revolve less around the university community, so the environment of the surrounding area is important. Do you need a city atmosphere to be productive? Or is your ideal location surrounded by forests and mountains or by a beach? Is being close to your family important? Imagine what it will be like living in the area during the times you are not doing research; consider what activities will you do and how often will you want to visit family.

While many of the PhD programs that accepted me had research that truly excited me, the only place I could envision living for five or more years was Boston, as the city I grew up near and whose environment and culture I love, and to be close to my family.

While location is more important than you think, the reputation and prestige of the university is not. In graduate school, the reputation of the individual department you are joining — and sometimes even the specific research group you work in — are more important. There, you will develop research collaborations and professional connections that will be crucial during your program and beyond. When searching for a job after graduation, other scientists will look at your specific department, the people you have worked with and the research you have done.

At the Asgard Irish Pub in Cambridge, Massachusetts, Andy Greenspon talks with fellow graduate students from Harvard and MIT at an Ask for Evidence workshop organized by Sense About Science. He grew up near Boston and chose to go to graduate school there.

7. Those time management skills you developed in college? Develop them further.

After surviving college, you may think you have mastered the ability to squeeze in your coursework, extracurricular activities and even some sleep. In a PhD program, time management reaches a whole new level. You will not only have lectures to attend and homework to do. You will have to make time for your research, which will include spending extended periods of time in the lab, analyzing data, and scheduling time with other students to collaborate on research.

Also, you will most likely have to teach for a number of semesters, and you will want to attend any seminar that may be related to your research or that just peaks your interest. To top it all off, you will still want to do many of those extracurricular activities you did as an undergraduate. While in the abstract, it may seem simple enough to put this all into your calendar and stay organized, you will find quickly enough that the one hour you scheduled for a task might take two or three hours, putting you behind on everything else for the rest of the day or forcing you to cut other planned events. Be prepared for schedules to go awry, and be willing to sacrifice certain activities. For some, this might be sleep; for others, it might be an extracurricular activity or a few seminars they were hoping to attend. In short, don't panic when things don't go according to plan; anticipate possible delays and be ready to adapt.

8. Expect to learn research skills on the fly – or take advantage of the training your department or career center offers.

This may be the first time you will have to write fellowship or grant proposals, write scientific papers, attend conferences, present your research to others, or even peer-review scientific manuscripts. From my experience, very few college students or even PhD students receive formal training on how to perform any of these tasks. Usually people follow by example. But this is not always easy and can be quite aggravating sometimes. So seek out talks or interactive programs offered by your department or career center. The effort will be well worth it when you realize you've become quite adept at quickly and clearly explaining your research to others and at outlining scientific papers and grant proposals. Alternatively, ask a more experienced graduate student or your advisor for advice on these topics. In addition, be prepared for a learning curve when learning all the procedures and processes of the group you end up working in. There may be many new protocols to master, whether they involve synthesizing chemicals, growing bacterial cells, or aligning mirrors on an optical table. In addition, the group may use programming languages or data analysis software you are unfamiliar with. Don't get discouraged but plan to spend extra effort getting used to these procedures and systems. After working with them regularly, they will soon become second nature. When I first started my job at Johns Hopkins, I felt overwhelmed by all the intricacies of the experiment and definitely made a few mistakes, including breaking a number of optical elements. But by the end of my year there, I had written an updated protocol manual for the modifications I had made to the experimental procedures and was the "master" passing on my knowledge to the next person taking the job.

9. There are no real breaks.

In a stereotypical "9-to-5" job, when the workday is over or the weekend arrives, you can generally forget about your work. And a vacation provides an even longer respite. But in a PhD program, your schedule becomes "whenever you find time to get your work done." You might be in the lab during regular work hours or you might be working until 10 p.m. or later to finish an experiment. And the only time you might have available to analyze data might be at 1 a.m. Expect to work during part of the weekend, too. Graduate students do go on vacations but might still have to do some data analysis or a literature search while away.

As a PhD student, it might be hard to stop thinking about the next step in an experiment or that data sitting on your computer or that paper you were meaning to start. While I imagine some students can bifurcate their mind between graduate school life and everything else, that's quite hard for many of us to do. No matter what, my research lies somewhere in the back of my head. In short, your schedule is much more flexible as a PhD student, but as a result, you never truly take a break from your work.

While this may seem like a downer, remember that you should have passion for the research you work on (most of the time), so you should be excited to think up new experiments or different ways to consider that data you have collected. Even when I'm lying in bed about to fall asleep, I am sometimes ruminating about aspects of my experiment I could modify or what information I could do a literature search on to gain new insights. A PhD program is quite the commitment and rarely lives up to expectations – but it is well worth the time and effort you will spend for something that truly excites you.

Contributor

Andy greenspon.

Educational resources and simple solutions for your research journey

How to Choose a PhD Research Topic

For most doctoral aspirants, starting on their PhD journey can be both exciting and challenging at the same time. It often begins with having to make a critical decision – choosing a research topic. A well-considered and relevant PhD research topic is crucial because it significantly impacts the overall success and quality of your Ph.D. research. While it may be perfectly normal for your topic to evolve as you progress in your research and make discoveries, the significance of the right PhD thesis topic cannot be overstated.  

The path to earning a PhD often lasts several years. To maintain the motivation and unwavering commitment throughout this journey, you must have a genuine interest in the subject matter you choose to explore. Your enthusiasm can be a driving force, leading you to overcome obstacles and persist in your academic pursuits.  

Let’s explore some methods to help you navigate the process of PhD topic selection, from brainstorming to finalizing your proposal.¹²³

• Focus on your field of study –  It is always a good idea to consider your past research experiences and what questions or problems intrigue you. Remember, while the subject of your PhD should definitely interest you, it should also contribute to the existing body of knowledge in your field. Deeply engaging with subjects that genuinely captivate you can lead to both academic excellence and personal fulfillment. Therefore, take time to evaluate trending PhD topics carefully – this can also help you make your choice. 
• Review relevant academic literature –  Immerse yourself in the literature of your field. Conduct thorough research to identify gaps, controversies, or unexplored avenues in current research. The existing body of knowledge can provide invaluable insights into potential research areas. 
• Assess available resources –  It is   critical to   assess the feasibility of your chosen topic. Consider the resources, data, and tools required to conduct your research. Ensure that you have access to the necessary resources and that your chosen PhD thesis topic aligns with your academic and financial capabilities. 
• Seek guidance from trusted advisors –  Consulting with experienced mentors and advisors is essential. They can provide guidance, suggest refinements to your topic, and help you avoid potential pitfalls. Their insights can be invaluable in shaping your research direction. 

Table of Contents

Formulating a Focused Research Question  

After PhD topic selection, the next step is to refine it into a straightforward research question. Your research question should be specific, relevant, and well-defined. It should be detailed enough to guide your research and provide clear direction while also leaving room for exploration and analysis. Consider the significance of your question – why is it important, and what contributions can your research make to the field?  

Creating a Research Proposal  

Once you have a well-defined research question, you will need to create a research proposal. This document is a blueprint for your entire research efforts. In the research proposal, you will outline the precise scope of your study, the objectives you aim to achieve, the methodology you intend to employ, and the anticipated outcomes of your research.  

Your research proposal typically goes through a thorough review and approval process involving critical evaluation and feedback from your academic advisors. This scrutiny ensures that your research is not only academically sound but also aligns with the standards and expectations of your academic institution. 

The approval of your research proposal marks the culmination of your efforts to refine your PhD research topic. This process finalizes your research topic and sets the stage for the beginning of your PhD journey. 

Evolution of Your PhD Research Topic  

It’s important to remember that choosing a PhD thesis topic can be daunting, and it’s okay for your topic to evolve as you progress through your doctoral studies. New findings and interesting discoveries may lead you in unexpected directions. This adaptability is a natural part of the PhD journey. 4

Your Ph.D. dissertation serves a dual purpose: enhancing your understanding of your field and making valuable contributions to it. While it doesn’t need to be groundbreaking, it must demonstrate originality and your research and argumentation skills. In essence, a Ph.D. program aims to identify scholars capable of making noteworthy contributions to their fields. Thus, your dissertation is a critical milestone in your academic career, and it all begins with the careful selection of your PhD research topic.5 

References:  

• How to Choose a Dissertation Topic For Your Doctoral Degree. Walden University website.  https://www.waldenu.edu/online-doctoral-programs/resource/how-to-choose-a-dissertation-topic-for-your-doctoral-degree  
• How to Choose a PhD Topic. Doctoral Journey, Grand Canyon University website; August 2020.  https://www.gcu.edu/blog/doctoral-journey/how-choose-phd-topic  
• How do you select a research topic for your dissertation or thesis? LinkedIn Higher Education article, November 2023.  https://www.linkedin.com/advice/1/how-do-you-select-research-topic-your-dissertation  
• How to decide on a PhD topic. The University of Queensland website, April 2022.  https://study.uq.edu.au/stories/how-to-decide-phd-topic  
• John Komlos, John Goldsmith. How does one choose a dissertation topic? IIT Delhi.  https://web.iitd.ac.in/~mamidala/HTMLobj-155/How_to_choose_a_PhD_topic.htm  

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Possible careers for phds in biomedical sciences.

Posted by Kim Petrie on Friday, December 11, 2020 in Path to Career Resources .

Sometimes it’s just nice to have a list of possibilities. Here’s a terrific list of career paths for PhDs in the biomedical sciences, compiled by Lauren Easterling at Indiana University School of Medicine. It’s nicely arranged by broad theme. See something you’re not familiar with? Check out our Beyond the Lab video and podcast series to see if we have recorded an episode with an alumnus who has pursued that career.

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Beyond the Lab: Data Science

• Youth Program
• Wharton Online

Wharton Stories

How to prepare a strong phd application.

Doctoral candidates and departmental coordinators at the Wharton School outline a few tips to help you navigate the PhD application process.

It’s no secret the application process can be intimidating. Where do you start? What exactly are schools looking for on your application? What materials do you need to submit? Doctoral candidates and departmental coordinators at the Wharton School have outlined a few tips to help you navigate the process.

Don’t Delay the Process

A successful PhD applicant starts thinking about their application months or even years before the deadlines. For Alejandro Lopez Lira , a third year student in Finance, the application process began a year before he actually submitted the paperwork. He said, “I spoke to my advisors way before, like one year before, about my letters of recommendation, where to apply, everything involved in the process.”

Each program has different requirements, which can make for a tedious process. Karren Knowlton , a third year in Management, said, “I took a little while to draft a personal statement. I had my mom, who teaches creative writing, and a few other people that I trust just read over it. Then you have to tweak it for different schools because they want slightly different things.”

Taking time to prepare your application is critical. Starting the process sooner rather than later gives you several advantages:

• It allows your letter of recommendation writers enough time in advance to thoughtfully prepare a letter that speaks to who you are as a PhD candidate.
• It gives you more time to review your materials, fix any errors, and proofread, proofread, proofread.
• Finally, it means a lot less stress when the deadline starts rapidly approaching. By planning ahead, you’ll have a much smoother process applying.

Get Letters of Recommendation

Prof. Matthew Bidwell , who previously served as the doctoral coordinator for the Management program , said a common mistake he sees are letters of recommendations from employers. Although he said it is impressive to see work experience, having an employer write a letter is not the best choice.

“We don’t pay very much attention to those because rightly or wrongly, we worry that they’re not looking for the kinds of things that we’re looking for,” he said. “If you have one, it’s not a disaster, but when you see people with two or three — most of their recommendations coming from their work — that kind of heightens our concern. You’re committing to a fairly specialized career, do you really know what that career entails?”

Instead, he suggests getting to know an academic who will be able to write a recommendation attesting to your ability to manage doctoral-level research and work.

Include Research/Work Experience in Your Field

Each program has a unique set of criteria to evaluate applicants, but several doctoral coordinators agree that some research and work experience in your field of interest will strengthen your application overall.

Prof. Fernando Ferreira , doctoral coordinator for the Business Economics and Public Policy and Real Estate programs, thinks work experience can be useful in demonstrating an applicant’s abilities. He said, “Any work experience after undergraduate school is important. If that experience is more related to research it’s even better, but work experience in general is always good.”

Prof. Guy David , doctoral coordinator for the Health Care Management & Economics program , thinks that work experience benefits applicants in terms of giving them a broader view of business. “Work experience creates retrospection about how the world works, how organizations make decisions, and how people function in various situations,” he said.

However, he warns that spending too much time away from an academic setting can have its drawbacks too. “It may lead people to start their PhD later when they are not in the habit of immersing themselves in rigorous studies and have a shorter horizons to develop a name for themselves,” he said.

Although having both research and work experience can strengthen your application, you will not be denied entry because you are lacking either.

Prof. Bidwell said, “I think research experience does give us some confidence that people have some idea about what it is that we do. In terms of work experience, I think we don’t have a strong view. We quite like work experience, but we also take people straight out of undergrad.”

Prepare for the Standardized Tests

Most PhD programs require students to take the Graduate Record Examinations (GRE). Having high test scores is a key part of an application as it tests skills learned over the course of many years in school. Quantitative skills are especially important when applying to doctoral programs in business areas. Much like any other standardized test, the GRE requires preparation.

Karren, who took the GRE twice to ensure her scores were high enough, offered advice to those who may be struggling. “I would absolutely recommend practicing the writing beforehand. Look up examples and have your outline structured,” she said. “So much of it is just getting the right structure and how you formulate your arguments so knowing what they’re looking for is key.”

Test prep can be time-consuming, but like anything else, practice makes perfect. There are multiple text books and online sites to help you prepare for the exam. Karren aimed to improve her math scores the second time she took the GRE and recommended this site to help strengthen math skills.

Taking advantage of resources to help you study can limit the number of times you need to take the GRE while ensuring you score high enough to remain in the applicant pool.

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Posted: August 4, 2017

• Admissions and Applying
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Doctoral Programs

Start your doctoral journey.

Whether you’re just starting your research on PhD programs or you’re ready to apply, we’ll walk you through the steps to take to become a successful PhD candidate.

Deciding to get a PhD

You might be surprised to find out what you can do with a PhD in business.

Is an Academic Career for You ? What Makes a Successful PhD Student

Preparing for the Doctoral Path

The skills, relationships, and knowledge you need to prepare yourself for a career in academics.

How the PhD Program Works How to Become a Successful PhD Applicant

Choosing the right program

What’s the difference between PhD programs? Find out how to choose one that fits your goals.

What to Consider When Choosing a Doctoral Program What Differentiates R1 Universities?

Starting an application

Tips for a successful application process.

Application Requirements Preparing Your PhD Application

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• How to Apply For a PhD: Step-By-Step

Written by Hannah Slack

Deciding to do a PhD is a big step and the road to submitting applications can seem long. To help you wade through all the information out there we’ve put together a simple step-by-step guide to the PhD application process.

Complete with top tips and links to further information, applying for a PhD has never looked simpler.

On this page

Step 1: choose your research area.

The first, and most obvious, step to applying for a PhD is to decide what research area you want to work in. Whether you’re looking for an Arts and Humanities PhD or a STEM one, each individual subject is made up of a vast array of research topics.

Most PhD courses will expect students to have a degree in a relevant field, although your previous qualifications do not have to be in the exact same discipline as the PhD you apply for. Students with a Masters in History, for example, may apply to research within the Religious Studies department. As long as the nature of research is similar and your chosen topic correlates with your experience, it’s possible to apply for a degree in a different department.

It’s worthwhile spending a bit of time considering what department you might want to join and what type of research you want to conduct.

Create a my FindAPhD account

Set-up an account to make your search easier. You can save programmes, send enquiries to institutions, view upcoming events, and see the latest news and updates, all in one place.

Step 2: decide what kind of PhD you want to do

There are two main types of PhDs: predesigned projects and self-proposed projects. The route you choose to take will mainly depend on your personal preference and situation.

While STEM subjects tend to have more predesigned projects, there are many students who choose to plan their own. Similarly, most Arts and Humanities PhDs are self-proposed but there are also many advertised projects out there.

Predesigned project

Advertised projects usually come in three different forms:

• Centre for Doctoral Training (CDT)
• Doctoral Training Partnership (DTP)

The main difference between these three types of PhDs is the level of industry experience offered to students, DTPs usually having the least industry involvement and iCASEs the most. However, all three do offer internship opportunities.

Some of these terms are used interchangeably, but you can read more about the differences between predesigned studentships in our guide.

The benefit of predesigned projects is that they are typically fully-funded four-year studentships. There are also many that come with an integrated Masters during the first year for those applying with only a Bachelors degree.

You also won’t have to research and plan your own project, which can save a lot of time.

However, as multiple students will be applying for the same advertised PhD opportunities, places can be competitive. Your choice of projects will also be limited to whatever research is currently advertised.

Design your own project

Many students in all fields choose to design and propose their own research project for PhD study. This option can be extremely rewarding as it allows students a lot more control over their work.

The downside is that not every self-proposed PhD is funded. While there are lots of funding opportunities available, there is not enough to cover the amount of PhD applications each year. Students may have to apply for part-time work or small grants throughout their studies.

Additionally, you will have to put in more time to your application as you need to design a viable PhD project.

For students choosing this route some additional steps are needed:

Step 2.1: research

To be able to propose a viable research project, you will need to spend a significant amount of time researching your chosen field. You may have already conducted some research during your previous degrees, giving you a good starting point.

The point of this step is to become familiar with the main academic arguments in your research area. You should then be able to identify a gap in the academic discussion which you will be able to fill in the timeframe of a PhD. This could include discussing an underused or new source base, criticising an academic argument or applying a new or different theory to the current discussions.

You should then look to identify a preliminary source base and decide how you intend to use the information.

Step 2.2: draft a research proposal

After completing a period of research, you should write up a draft research proposal. While this won’t be your final piece for submission with your application, having a draft can be useful when it comes to step three, contacting prospective supervisors. You can find out more about how to write a good PhD proposal in our guide.

Step 3: contact prospective supervisors

Once you have decided on which projects you intend to apply for, or drafted a research proposal, it’s time to reach out to prospective supervisors. This is an important step as it allows you to gain more insight into how your potential PhD might go. Our top tips for getting in contact with potential PhD supervisors can help you to reach out.

For predesigned projects the supervisor will be listed in the advertisement. By contacting them you can introduce yourself and discuss the research in more detail.

If you are proposing your own PhD research then you will have to search for potential supervisors yourself. The research stage of step two should mean that you have a good grip on the prominent academics in your field. This is a good place to start. It is also worthwhile looking through staff lists on university websites to find other experts who are perhaps earlier on in their career.

Contacting prospective supervisors is a good opportunity to receive feedback on your ideas and research proposal. You should first ask if they are able to take a look at your draft after briefly explaining who you are and summarising your project. Any feedback can be extremely useful as their expertise and experience could help them notice any holes in your proposal that you should consider and fix before applying.

Receiving feedback from an inhouse academic will also help you tailor your proposal specifically to the expertise of your prospective institution and supervisor expertise.

Step 4: check entry requirements

The next major step is to check the entry requirements of the institution or project. Most PhD applicants should have a Masters degree in a relevant field as well as a history of strong academic achievement.

PhD without a Masters

Some funded studentships will allow Bachelors graduates to apply. There is also the possibility to apply for an integrated programme that will include a year of Masters level training before beginning PhD research.

International applicants

If you are applying as an international student, make sure to check what visas may be required and how to obtain them. To study in the UK, international applicants will need a Student Route visa. To apply for this, you will need:

• a confirmation of acceptance into a university
• proof of sufficient funds
• proof that you meet the English language requirements

Make sure to check beforehand the eligibility criteria of the visa you need to apply for in case you need to undertake a language exam or entry test .

Step 5: check fees and potential funding options

Once you have decided which PhD opportunities you want to apply for, and know that you’re eligible, it’s time to look more deeply at the financial practicalities. PhD study is not cheap and often has many unforeseen costs such as books, equipment, travel and conferencing fees. Knowing your potential funding options can help you plan ahead.

Funding options

Practically all PhD applicants hope to be fully-funded. If you are applying for an advertised project then you will typically receive full funding if successful. This funding most commonly comes from Research Councils who outline their own restrictions on how the money can be used and deadlines for thesis submission. It’s a good idea to read the funder’s terms and conditions and make sure you understand what would be required of you as a researcher.

Those designing their own PhD are likely to apply for Research Council funding. Unfortunately, there is only a set amount of money available from Research Councils for self-proposed projects and so some PhDs are unsuccessful in their application. However, this does not mean you can’t go on and complete a successful PhD.

As receiving fully-funded studentships can be very competitive, it’s important to know other potential sources of funding. These can include:

• Universities – Many institutions offer their own funding , ranging from small fee discounts to full studentships. Make sure to research any financial support your chosen universities may offer and what you and your project could be applicable for.
• Charities, trusts and societies – some independent organisations offer to partially (and sometimes fully) fund PhD students if their research correlates with the groups’ interests. Support is available for a large variety of subjects so make sure to do some research.
• PhD loans – The UK government offers doctoral loans to English and Welsh PhD students who were unable to secure a full studentship. This will not usually cover the full cost of a PhD. Students wishing to self-fund with the help of a PhD loan will potentially have to take up part-time work such as teaching within the university.

PhD funding

Find out more about PhD funding options and how it works on FindAPhD.com.

Step 6: prepare to apply

Now that you have thought about the practicalities of PhD study you can start to gather the required documents to apply.

The most important thing to note down when starting to prepare is the PhD application deadlines. Many universities will have different deadlines and if you are applying for funding, applications may need to be submitted even earlier.

It’s a good idea to aim to submit your application with plenty of time to spare, taking into account any difficulties that might arise gathering together the relevant paper work.

The documents you need for your application will depend on the university and funding you are applying for. Some things you may be asked to provide are:

• Personal statement / cover letter
• Research proposal
• Details of at least two referees (make sure to contact them beforehand so they know what you are applying for and why)
• Academic transcript

International students may also need to provide:

• Proof of language proficiency
• Proof of funds
• Student visa

Step 7: submit your application

Once you have written, polished and gathered all the documents you need, it’s time to apply. Most PhD applications are done through the university’s application portal. Many also allow you to start your application and come back to it at a later date, so don’t feel like you have to submit everything all in one go.

If you are applying for funding separately make sure to read the details of how to apply on the funder’s website. Typically, Research Council funding is applied for with the same application you submit to the university. Other sources of funding may have a different application system.

Still looking for the perfect PhD course?

Head over to our PhD course listings to keep up to date with the latest opportunities.

Our postgrad newsletter shares courses, funding news, stories and advice

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We've answered some of the most frequently asked questions about PhDs, covering course types, applications, funding and the benefits of further study.

Getting ready to apply for a PhD? Our guides explain research proposals, references and entry tests for doctoral programmes.

Understand what a successful PhD research proposal needs to include and how to go about writing one for your project application.

Our guide explains how to contact a potential PhD supervisor to discuss your proposal or ideas with them before applying.

A checklist of the things you'll need to do when making an international PhD application, from meeting the entry requirements to sorting out your visa.

What documents you need for a complete study abroad application, what they are and what they should and should not include.

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How to decide on a PhD topic

Study tips Published 5 Apr, 2022  ·  4-minute read

Whether you’re diving right into your doctorate after a master’s degree or honours year, or you’re returning to study after a few years out in the field, working out how to choose a research topic for your PhD is an essential first step. We got some tips from two of our PhD candidates, Sarah Kendall and Chelsea Janke.

Some Doctor of Philosophy candidates are lucky. They start a PhD having already discovered their niche interest area, which means they never need to wonder how to choose a PhD topic.

Does this mean there’s something wrong with you if you don’t already have your thesis locked in?

Not at all.

Many students start their PhD journey with just a pure passion for research – a love for testing theories and making new discoveries – and figure out their specific research topic while working on their proposal . If you’re in this camp, or if you haven’t refined your thesis just yet, these tips can help you get there.

Your PhD will take 3-4 years, so it's important that you choose something you're genuinely interested in.

How to choose a PhD topic

Sarah is the first to admit that choosing a PhD thesis topic is daunting. Her thesis examines lawyers’ approaches to prosecuting and defending domestic and family violence cases, but this topic didn’t come to her overnight.

“This can be really hard,” says Sarah.

“It took me years to decide on a PhD topic, and even then, it continued to change after starting my PhD.”

Chelsea, whose research explores ways to keep soil healthy while reducing environmental impact, agrees that your initial thesis may not necessarily stay the same throughout your PhD.

“Keep in mind that, as you progress through your PhD, your topic may change as you make new findings and discover some interesting things,” she says.

“This is fairly normal and is often why PhD topics aren’t always set in stone at the start.”

Remember this if you find yourself getting frustrated with how long it’s taking to pin down your research topic. You’ll be spending significant time ( at least 3 years ) researching this topic, so it’s reasonable to take a while on this decision. Make sure you land on a topic that truly inspires you, as you’ll need that inspiration to keep you motivated for the long haul.

With that said, though, there’s nothing wrong with picking a topic you’re 99% sure of and getting started sooner. As Sarah and Chelsea both say, adapting your thesis along the way is often part of the PhD journey.

Read, read, read

Identify the things that really spark your interest and where you can find research gaps – that is, where there are still things we don't know.

Chelsea believes choosing your research topic begins with, well, research .

“Read widely on the general field that you’re interested in,” she says.

“Identify the things that really spark your interest and where you can find research gaps – that is, where there are still things we don’t know.”

Sarah agrees and acknowledges that sometimes this prior research can even translate into a separate project or even a degree.

“Do some research into the areas that interest you – this could take the form of an honours or other research project, or even a mock project that you do in your spare time,” she says.

“This will help you to decide your level of interest in the topic.”

Consider your subjects and speak with academics

Sarah recommends thinking about the courses from your current or previous program, as these can shine a light on what aspects of your field ignite your curiosity.

“Consider the subjects that you really enjoyed in your previous studies or those topics that you find really enjoyable to just learn about in your spare time,” she says.

“Narrow this down to a few areas, even if these are still pretty broad, then talk to as many academics as possible who do research in those areas. This is a really great way of finding out more about what’s topical in the area and what a potential project could look like.”

If you already know who you’d like to be your PhD supervisor, they are the obvious person to speak with first about refining your research topic. If not, learn how to find the right supervisor .

Check for openings on existing projects

Sometimes the best way to choose a PhD topic is to let the PhD topic choose you instead. Many academics keep open spots in their research projects for potential candidates to fill, providing opportunities for students to pursue their own thesis while assisting in a larger research team. We call these earmarked PhD projects .

In fact, this is what ended up helping Sarah select her thesis topic.

“Keep an eye out for projects that are being advertised by academics,” says Sarah.

“You might find one that fits with your area of interest, saving you much of the trouble of having to decide on your specific topic – this is how I came to be doing the project I’m currently doing!”

View available earmarked PhD projects at UQ

Ready to start researching your chosen topic? Discover the next steps for your PhD application.

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How to write a good PhD proposal

5-minute read

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10 things you need to know before starting a PhD degree

So you want to do a PhD degree, huh? Here we've got everything you need to know about getting started.

So you want to do a PhD degree, huh? Are you sure about that? It’s not going to be an easy decision, so I’ve put together a list of 10 things you need to know before starting a PhD degree. Oh, and don’t panic!

I have recently graduated from the University of Manchester with a PhD in Plant Sciences after four difficult, but enjoyable, years. During those four years, I often felt slightly lost – and there was more than one occasion on which I didn’t even want to imagine writing up my thesis in fear of delving into fits of panic.

On reflection, I realise that – to quote a colleague – commencing my PhD was like “jumping in the deep end with your eyes closed.” If only I’d known to take a deep breath.

1. Are you sure you want to do a PhD degree?

Let’s be under no false impressions, completing a PhD isn’t easy. There will be times when you feel like Wile E Coyote chasing after the Roadrunner – a little bit out of your depth a lot of the time. It’s four years of your life, so make sure it is what you really want to do.

If you want to pursue a career in science, a PhD isn’t always necessary.

It is possible to make great inroads into industry without a doctoral degree. That said, a PhD can also be a very useful qualification with many transferable skills to add to your CV.

By the time you’ll have finished, you can include essentials such as time management, organisational skills, prioritising workloads, attention to detail, writing skills, presenting to an audience – and most importantly – resilience, to name but a few.

2. Choose your project, and supervisor, wisely.

This is  very  important.

Time after time, our experienced scientists at EI, including Erik Van-Den-Bergh (and I agree) say, “ make sure you’re extremely passionate about exactly that subject. ” When I saw the PhD opening that I eventually was offered, I remember being demonstrably ecstatic about the project before I’d even started it.

I was always interested in calcium signalling and organised a meeting with my potential supervisor immediately, which (to quote Billy Connolly) I leapt into in a mood of gay abandon.

Not only does this help you to keep engaged with your project even through the painstakingly slow times, it also greatly enhances your ability to sell yourself in an interview. If you can show passion and enthusiasm about the project and the science then you’ll be that one step ahead of other candidates – which is all the more important now that many studentships are competitive.

You have to  be the best  out of many, often exceptional candidates.

However, as important as it is to be passionate about your project, make sure that the person who will be supervising you is worthy.

Does your potential supervisor have a prolific track record of publishing work? What is the community of scientists like in the lab you may be working in? Are there experienced post-doctoral scientists working in the lab? Who will your advisor be? Is your supervisor an expert in the field you are interested in? Is the work you will be doing ground-breaking and novel, or is it quite niche?

There is nothing more frustrating – and I know many PhD degree students with this problem – than having a supervisor who is rarely there to talk to, shows little interest in your work, and cannot help when you are struggling in the third year of your project and some guidance would be much appreciated.

Personally, and I was very lucky to have this, I think it’s incredibly useful to have two supervisors. My PhD degree was split between the University of Manchester and the Marine Biological Association in Plymouth. Between my supervisors, I had two people with expertise in different fields, who could give me some fantastic advice from different perspectives. This also meant that I had two people to check through my thesis chapters and provide useful comments on my drafts.

Make sure you are passionate about your subject before taking it to PhD level. And by passionate I mean  really  passionate.

For a start, you will most likely have to write a literature review in your first three months, which if done well will form the main bulk of your thesis introduction and will save you a lot of stress and strain when it comes to writing up.

At the end of your first year, you will have to write a continuation report, which is your proof that you deserve to carry on to the end of your three or four years. This doesn’t leave much time for lab work, which means time management is incredibly important. If you think you’ll be able to swan in at 11 and leave at 3, think again.

Fundamentally, never, ever rest on your laurels! As tempting as it may be to slack-off slightly in the second year of your four year PhD, don’t.

4. Be organised.

This is a no-brainer but still, it’s worth a mention. Take an hour on a Monday morning to come up with a list of short-term and long-term goals. You’ll probably have to present your work at regular lab meetings, so it’s always worth knowing what has to be done (lest you look a pillock in front of the lab when there’s nothing to show for your last two weeks.)

It’s always good to have a timeline of what will be done when. If you have a PCR, maybe you can squeeze in another experiment, read a few papers, start writing the introduction to your thesis, or even start collecting the data you already have into figures.

The more good use you make of your time, the easier it’ll be to finish your PhD in the long run. Plus, it’s lovely to sit back and look at actual graphs, rather than worry about having enough to put into a paper. Once you’ve typed up your data, you’ll realise you’ve done far more than you had anticipated and the next step forward will be entirely more apparent.

5. Embrace change – don’t get bogged down in the details.

Felix Shaw – one of our bioinformatics researchers at EI – put it best when he said, “ it felt like I was running into brick walls all the way through [my PhD]… you’d run into a brick wall, surmount it, only to run straight into another. ”

You’ll find that, often, experiments don’t work. What might seem like a great idea could turn out to be as bad as choosing to bat first on a fresh wicket on the first day of the third Ashes test at Edgbaston. (Yeah, we don't know what that means either - Ed).

Resilience is key while completing your PhD. Be open to change and embrace the chance to experiment in different ways. You might even end up with a thesis chapter including all of your failures, which at the very least is something interesting to discuss during your  viva voce .

6. Learn how to build, and use, your network.

As a PhD student, you are a complete novice in the world of science and most things in the lab will be – if not new to you – not exquisitely familiar. This matters not, if you take advantage of the people around you.

Firstly, there are lab technicians and research assistants, who have probably been using the technique you are learning for years and years. They are incredibly experienced at a number of techniques and are often very happy to help show you how things are done.

There are postdocs and other PhD students, too. Not only can they help you with day-to-day experiments, they can offer a unique perspective on how something is done and will probably have a handy back-catalogue of fancy new techniques to try.

There are also a bunch of PIs, not limited to your own, who are great to talk to. These people run labs of their own, have different ideas, and might even give you a job once you’ve completed your PhD.

Don’t limit yourself to the labs directly around you, however. There are a massive number of science conferences going on all around the world. Some of them, such as the Society of Biology Conference, take place every year at a similar time in different locations, attracting many of the leaders in their respective fields.

If you are terrified by the prospect of speaking at a full-blown science conference and having your work questioned by genuine skeptics, there are also many student-led conferences which will help you dangle your fresh toes in the murky waters of presenting your work.

One such conference, the Second Student Bioinformatics Symposium, which took place at Earlham Institute in October 2016, was a great place for candidates to share their projects with peers, who are often much more friendly than veteran researchers with 30 year careers to their name when it comes to the questions at the end of your talk.

Another great reason to attend conferences, of course, is the social-side too – make the most of this. You never know who you might meet and connect with over a few drinks once the talks are over and the party commences.

7. Keep your options open.

You should be aware that for every 200 PhD students,  only 7  will get a permanent academic post , so it’s  incredibly unlikely that you’ll become a Professor  – and even if you make PI, it probably won’t be until your mid-forties.

You may also, despite having commenced along the academic path, decide that actually, working in a lab environment isn’t for you. Most PhD graduates, eventually, will not pursue an academic career, but move on to a wide range of other vocations.

It might be that Science Communication is more up your street. This was certainly the case for me – and I made sure that I took part in as many public engagement events as possible while completing my PhD. Most Universities have an active public engagement profile, while organisations such as STEM can provide you with ample opportunities to interact with schools and the general public.

You might also consider entrepreneurship as a route away from academia, which might still allow you to use your expert scientific knowledge. There are a variety of competitions and workshops available to those with a business mind, a strong example being Biotechnology YES.

I, for example, took part in the Thought for Food Challenge, through which I have been able to attend events around the world and meet a vast array of like-minded individuals. Many of the participants from the challenge have gone on to set up successful businesses and have even found jobs as a result of the competition.

8. Balance.

Remember that you still have a life outside of your PhD degree – and that this can be one of the greatest opportunities to make amazing friends from around the world.

A science institute is usually home to the brightest students from a variety of countries and can provide a chance to experience a delightful range of different people and cultures. Don’t just stick to the people in your lab, go to events for postgraduate students and meet people from all over campus.

There are usually academic happy hours happening on Fridays after work where you can buy cheap beer, or some lucky institutions even have their own bar. At Norwich Research Park, we not only have the Rec Centre, along with bar, swimming pool, calcetto, samba classes, archery, and a range of other activities, but there are also biweekly “Postdoc pub clubs” which are very fun to join on a Tuesday evening.

Maintain your hobbies and keep up with friends outside of your PhD and you’ll probably find it’s not that gruelling a process after all.

Plus, the people you meet and become friends with might be able to help you out – or at least be able to offer a sympathetic shoulder.

9. Practical advice.

If, after reading all of this, you’re still going to march forth and claim your doctorhood, then this section should be rather useful.

Firstly, make sure your data is backed up. It’s amazing how many people don’t do this and you’d be bonkers not to. Keep your work saved on a shared drive, so that if your computer decides to spontaneously combust upon pressing the return key, you won’t have lost all of your precious work – or have to go through every one of your lab books and type it all up again.

Secondly, don’t leave your bag in the pub with your half-written thesis in it. I did this, the bag was fine, I was in a state of terror for at least half an hour before the kind person at Weatherspoons located said bag.

Thirdly, read. Read broadly, read anything and everything that’s closely related to your project – or completely unrelated. It’s sometimes amazing where you might find a stroke of inspiration, a new technique you hadn’t thought of … or even in idea of where you might like to go next.

Finally, ask questions – all of the time. No matter how stupid it might sound in your head, everyone’s probably been asked it before, and if you don’t ask, you don’t get.

You’ll probably look far less stupid if you just ask the person standing next to you how the gradient PCR function works on your thermal cycler rather than standing there randomly prodding buttons and looking flustered, anyway.

10. Savour the positives.

At the end of all of this, it has to be said that doing a PhD is absolutely brilliant. There’s no other time in your life that you’ll be this free to pursue your very own project and work almost completely independently. By the time you come to the end of your PhD, you will be the leading expert in the world on something. A real expert! Until the next PhD student comes along …

Related reading.

A PhD, is it worth it? Just ask our students

The realities of doing a PhD

My advice for PhD students? See what bites

COVID and my PhD: to lockdown and back

How does a PhD work and how to find the right one

Building the confidence to take on a PhD

PhD life, 10 things we learned in our first six months

What’s the third year of a PhD like? Tips for navigating your PhD

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Reasons to do a PhD or research degree

Is research right for you?

Discover the benefits of getting a PhD or research degree and how it can boost your career.

Do you love learning, want to keep researching or hit the heights of your field of expertise?

PhDs and research degrees help you start or continue your research in a field you're passionate about. You can decide what you work on, how you work on it and how you get there, with support and guidance from a supervisory team.

Make a world-first discovery, create innovation with lasting impact or shine a new light on important topics.

Whether you've just finished your postgraduate degree, in the workforce or returning to uni after a break, a research degree gives you a lot of options.

Jump to section:

Questions to ask yourself.

Don’t just take our word for it – check out some of our Student Stories to see the great experience our students had at uni.

For me Portsmouth bridged the gap between academia and practical work, from leading my own firm (Alexandrite Decisions) to founding a charity organisation for cancer patients support.

Rania Azmi, Goal Programming Research Doctorate

1. Passion for research

If you simply love learning and have a passion for discovering new things then it's a good sign a research degree is for you.

You'll pick a topic you're interested in and have the freedom to dive deep into the heart of a problem.

Draw on the years of research in your field, forge your own findings or perspective and make your contribution to a body of exceptional research.

2. Become an expert in your field

Build on your knowledge from your Master's degree by engaging with complex topics in a more specialised field of your choice.

You'll be able to learn more about what you're passionate about and give you the tools to make meaningful contributions to specific research fields.

You'll dive into key areas and challenges in your field, developing your theoretical approach and applying it through your research.

Or you could look at conducting interdisciplinary research. Blend theories, approaches and expertise across fields and universities to create brand new, world-leading research.

3. Put your studies into practice

If you want to start applying what you learned in your studies then a research degree is a great way to do it.

You'll work independently in gathering resources and research. You'll develop sharp time management skills, share your findings with your peers and develop your work together.

You'll hone your communication skills so you can discuss complex topics both written and verbally to experts and everyday people alike.

You'll develop your interpersonal skills, working with professional staff, peers, academics and others. Become a master of taking on feedback as you refine your research.

Writing an extended report or essay takes time and skill. Identifying an objective, working in the lab or forging an argument and making your case with evidence takes talent. You'll end up a technical expert and writer no matter what field you're in.

4. Learn with engaged peers

During your research degree, you and your peers are all studying to get better at what you do. You'll learn with motivated researchers bringing their own perspectives and experiences to the same problems.

You'll build a solid study group to push and encourage each other to develop. You'll also gain new insights from your classmates that can help shape your learning.

5. Boost your career

A research degree is a great way to become a subject matter expert or researcher.

A research-based degree is the most direct pathway to an academic job at university. You'll get the skills you need to compete in the university sector. After you graduate you can look at becoming a tutor, researcher or lecturer. Most universities offer post-doctoral research fellowships where you can get paid to hone your skills, carry on researching and get your academic career rolling.

Some jobs require a Master's or PhD and generally pay very well in the private and public sector. You could:

• work in the public or private sector in industrial research and development
• advise on government policy to make an impact on your local region or country
• become a communications expert for your field and share complex research in clear, everyday fashion

6. Networking opportunities

PhDs and research degrees are a great chance to expand your network and meet diverse people with similar interests, knowledge and passion.

You'll have the chance to attend conferences, seminars and workshops in different cities or countries. Gain new insights and build connections with other researchers and experts across borders.

Networking with coursemates, colleagues and other academics helps expand your knowledge base and balance the solitude that can often come with a research life. Having a network is also incredibly helpful in finding and applying for funding and looking for work in the future.

7. New city, new experiences

Studying for a PhD or research degree might mean moving cities or even countries. If you've been wanting a change of setting along with your career path it's a great opportunity to give both a try.

If you're an international student, studying in a different country gives you the chance to graduate with both fantastic life experiences and a great qualification.

Portsmouth is a welcoming, student-friendly city – one where you'll meet people from all around the world, and have the chance to make connections with people in a whole new environment.

See why Portsmouth is a great place to live

Since starting my PhD, I have been lucky enough to publish twice and visit three different conferences, one of which was held at Cornell University. These opportunities will prove invaluable in my career going forwards, in academia.

Robert Lawrence, PhD Molecular Microbiology

Just like any course, the benefits you'll get from a research degree depends on what you want to get out of it. When you're weighing up your options there are some important questions you should ask yourself to make sure it's right for you.

1. Is this subject something I'm passionate about?

Studying a research degree is a multi-year time commitment. If you're excited by the idea of spending a significant period of time dedicated to one subject, that's a good sign you're ready.

Research degrees often involve a lot of independent work, so if you're only partly interested in the subject, you might find yourself losing interest. That can make meeting your own expectations more difficult.

Is learning about and working in this field something that you can see yourself in for the next 5-10 years? And where do you want to be in that timeframe? It's important not to study just so you can put off bigger life decisions.

2. Do I need a research degree to follow my passion?

There are many different jobs or careers in every field. Not all of them require you to have a research Master's or PhD.

If you want to contribute to a specific industry or area, do you already have some skills and knowledge you can apply in it? If not, what skills or knowledge will a research degree give you?

3. Am I ready for more uni?

If you've finished your Bachelor's or Master's degree and are looking at your next options, a research degree is an option that keeps things familiar. For some students, if you've spent the last 3-4 years studying you might want to try something different.

It depends on who you are, what you care about and what you want to do with your life. If you finished your degree and you're mostly relieved it's over then jumping right back into study may not be the best fit for you.

Remember that you can always go to uni again later. Plenty of graduates spend a few years working before coming back to upskill, retrain or dive into their passion. In a lot of cases, what you've learned in your work experience will make you a better student when you go back to it.

4. Have I found the right supervisor?

Every research student has at least one supervisor. They're there to support and guide you as you develop your ideas and compile your research

Having the right supervisor can be the difference between making your research good, great or excellent. If they're running or part of a research centre or group you may have greater access to networks and resources

It's best you explore supervisors you can work with , which might mean checking out multiple universities and reaching out to them directly. Usually, their profile will say if they're taking on new students and they're happy to get back to you by email.

As it is a PhD I have formed my course myself, but having a supervisor who is well-versed in my subject area is the most unique part of my work here, as no one else is approaching the subjects we look at in a similar way

Beatrice Ashton-Lelliott, PhD English Literature

5. Can I afford it?

Before you decide on a research degree it's important to think about the costs involved.

If you're a UK national applying for an MPhil or MRes course, you might be eligible for a Government Postgraduate Master's Loan  which you can use to fund your tuition fees, living costs and other costs for a Master's course.

If you're an international student you'll need to plan out how you can cover your costs and fund yourself while you're studying.

When considering a PhD there are funded and non-funded options:

• If you've got an idea that aligns with an academic's field of expertise, you can contact them directly
• Look to external funding from the government or an independent research body
• Universities will offer funded PhD opportunities but these may be limited
• Start a PhD without funding support

If you're currently working you may need to adjust your working hours or potentially look for part-time work. You might have less money to play with if you're studying full-time and working on the side.

If you're moving cities or countries there are other costs you'll need to consider. You'll need to factor in things like the initial cost of moving and your deposit if you're renting a place.

Find out more

Our research degrees subject areas.

Take your expertise further by studying for a PhD or other research degree at the University of Portsmouth. Explore the subject areas you can study & get started on your research journey.

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Find out how you can fund your postgraduate research project, with options including loans, bursaries, and scholarships.

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5 routes to getting a Doctorate

While most of those studying for a PhD take the PhD by thesis pathway, there are five viable routes to achieving a Doctorate, with both full-time and part-time options available

PhD by thesis

This is the most common means of getting a Doctorate. Over the three or four years of research at university, your PhD supervisor will support you as you aim to produce a thesis based on your research proposal .

A thesis is typically 60,000-90,000 words in length - although this can vary between institutions. For instance, the University of Glasgow's College of Social Sciences expects a thesis to be 70,000 to 100,000 words including references, bibliography and appendices, while the University of Cambridge has set an upper limit of 80,000 words.

Once completed, you'll need to defend your PhD thesis in front of a panel of examiners during your viva voce .

Doctorate by publication

This route involves submitting previously published work - such as books, book chapters and journal articles, which together form a coherent body of work and show evidence of an original contribution to a particular field of study.

The PhD by publication route is often taken by mid-career academics that haven't had the opportunity to undertake a standard Doctorate degree.

Generally, a minimum of five to eight published pieces are required, but this varies between institutions and depends on their length. The published work will be assessed to the same rigorous standards as a traditional PhD by thesis.

You must also provide a written supporting statement, which typically ranges from 5,000 to 15,000 words.

For instance, the University of Westminster asks for a commentary of 5,000 words (science and technology subjects) or 10,000 words (arts, social sciences and humanities). On the other hand, Queen Margaret University Edinburgh requires 12,000 to 15,000 words on the rationale and theoretical context for the portfolio of published work.

The work will then be presented to an academic committee. A supervisor will assist you with selecting which publications to submit, as well as guidance on the supporting statement.

Some universities accept only their own graduates for a PhD by publication, while others restrict this route to their academic staff. In general, you should have graduated from your first degree at least seven years ago to be eligible.

For example, The University of Manchester has published its own Guidance for the PhD By Published Work , with eligibility only extending to current members of staff.

Professional Doctorate

This type of Doctorate includes a significant taught component and a smaller research project, and is geared primarily towards current professionals in vocational sectors such as:

• engineering and manufacturing
• teaching and education .

Professional Doctorates are often taken on a part-time basis and can last between two and eight years. Like their standard PhD counterparts, they usually begin in October or January.

While you won't typically be looking to get an academic job , your research is expected to contribute to theory as well as professional practice. Projects often revolve around a real-life issue that affects your employer.

Several professional Doctorates, such as the Doctorate in Clinical Psychology (DClinPsy), are accredited by a professional body - for instance, the Health & Care Professions Council (HCPC) and The British Psychological Society (BPS) - and may also lead to a professional qualification .

Common titles for graduates of professional Doctorate degrees include:

• Doctor of Business Administration (DBA)
• Doctor of Education (EdD)
• Doctor of Engineering (EngD)
• Doctor of Medicine (MD).

Unlike many professional Doctorates, the EngD is typically offered as a full-time course and is aimed at young engineering graduates with little or no professional experience.

Integrated PhD

This four-year qualification, also known as the New Route PhD, involves studying a one-year research Masters degree (MRes) before progressing onto a three-year PhD.

Offered by a select number of universities across the UK, integrated PhDs are supported by the government and the British Council through UK Research and Innovation (UKRI) .

Visit Research Council funding for further information on research and funding for different types of PhD.

The integrated PhD involves a combination of taught materials, practical experience and advanced research. This allows you to learn subject-specific methodologies, while building the transferable skills that will enable you to become a leader in your chosen profession.

Institutions can also develop personalised integrated PhD programmes to meet each student's needs. For example, universities may offer you the opportunity to gain a postgraduate certificate (PGCert) in Learning and Teaching in Higher Education - perfect if you're considering a career as a higher education lecturer .

Online/distance learning PhD

As PhDs are based primarily on independent research rather than time spent in lectures and seminars, distance learning has always been a viable route for many Doctoral students.

PhDs by distance learning offered by course providers such as The Open University are therefore a good option to consider if you've got family or work commitments or are an international student - as this gives you the chance to undertake Doctoral research without having to live close to your chosen institution. It's also a suitable mode of study if your subject requires you to be based in a specific location away from the university.

For the most part, you'll be in touch with your supervisor by phone, email or Skype/Zoom. You'll need to bear in mind that even if you opt for this form of research, you'll generally still need to attend university for one or two weeks of each academic year for meetings and to receive research skills training. Your final exam may be undertaken either face-to-face or virtually.

With online PhDs, you can usually register as a full or part-time student. The level of fees you pay varies between institutions - some charge the same as for a standard PhD while others offer a reduced rate.

Check that any funding you plan to apply for is available to distance learning students, as this isn't always the case.

Search for online/distance learning PhDs .

Find out more

• Discover what is a PhD?
• Sort out funding for postgraduate study .
• Consider what to do after completing your PhD .

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Students in our PhD programs are encouraged from day one to think of this experience as their first job in business academia—a training ground for a challenging and rewarding career generating rigorous, relevant research that influences practice.

Our doctoral students work with faculty and access resources throughout HBS and Harvard University. The PhD program curriculum requires coursework at HBS and other Harvard discipline departments, and with HBS and Harvard faculty on advisory committees. Faculty throughout Harvard guide the programs through their participation on advisory committees.

How do I know which program is right for me?

There are many paths, but we are one HBS. Our PhD students draw on diverse personal and professional backgrounds to pursue an ever-expanding range of research topics. Explore more here about each program’s requirements & curriculum, read student profiles for each discipline as well as student research , and placement information.

The PhD in Business Administration grounds students in the disciplinary theories and research methods that form the foundation of an academic career. Jointly administered by HBS and GSAS, the program has five areas of study: Accounting and Management , Management , Marketing , Strategy , and Technology and Operations Management . All areas of study involve roughly two years of coursework culminating in a field exam. The remaining years of the program are spent conducting independent research, working on co-authored publications, and writing the dissertation. Students join these programs from a wide range of backgrounds, from consulting to engineering. Many applicants possess liberal arts degrees, as there is not a requirement to possess a business degree before joining the program

The PhD in Business Economics provides students the opportunity to study in both Harvard’s world-class Economics Department and Harvard Business School. Throughout the program, coursework includes exploration of microeconomic theory, macroeconomic theory, probability and statistics, and econometrics. While some students join the Business Economics program directly from undergraduate or masters programs, others have worked in economic consulting firms or as research assistants at universities or intergovernmental organizations.

The PhD program in Health Policy (Management) is rooted in data-driven research on the managerial, operational, and strategic issues facing a wide range of organizations. Coursework includes the study of microeconomic theory, management, research methods, and statistics. The backgrounds of students in this program are quite varied, with some coming from public health or the healthcare industry, while others arrive at the program with a background in disciplinary research

The PhD program in Organizational Behavior offers two tracks: either a micro or macro approach. In the micro track, students focus on the study of interpersonal relationships within organizations and the effects that groups have on individuals. Students in the macro track use sociological methods to examine organizations, groups, and markets as a whole, including topics such as the influence of individuals on organizational change, or the relationship between social missions and financial objectives. Jointly administered by HBS and GSAS, the program includes core disciplinary training in sociology or psychology, as well as additional coursework in organizational behavior.

Accounting & Management  

Business economics  , health policy (management)  , marketing  , organizational behavior  , strategy  , technology & operations management  .

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What Can You Do With a PhD?

Why Do a PhD? Benefits and Career Directions

Are you thinking about a PhD as the next stage in your educational and professional development? It’s an exciting road to travel with many potential benefits and opportunities. But you have to earn it first so considering what’s involved is important.

Requirements for a PhD award vary greatly globally and from institution to institution. PhD applicants are expected to have gained at least an Honours degree and sometimes a Master’s degree to be eligible to apply for a PhD programme.

It’s best to find out as much as possible about not only what you can expect during the PhD process but also what will be expected of you. Will the commitments in terms of time, effort and money prove worthwhile? Identifying the pros and cons will help you to weigh up whether this is the right step for you.

The on-going impacts of COVID -19 have to be taken into account. Not only have teaching and learning practices altered in Higher Education but so have ways of working and connecting with each other as technological change advances more rapidly. Sudden shifts and uncertainties mean that flexibility must be factored into any PhD planning, such as supervision or research having to be carried out online.

This article will outline possible career paths and prospects that can follow on from having a PhD as well as the benefits during the process.

First of all ask yourself- Is a PhD right for me?

Do some self-assessment:.

• what your educational experiences and achievements are up to now
• identify what you liked and disliked
• what you were good/skilled at, what you found difficult

Talk to others

Whilst there is no ‘typical’ PhD experience as everyone’s paths differ, it’s helpful to talk to those who have done or are doing a PhD about what is involved. You can make contacts through networks and online forums and find out more about their experience. Read articles and other relevant documents including university publications plus online sources. There is a wide range of websites offering case studies of career stories from what people have done with their PhD.

What parts of doing a PhD appeal to you?

It could be spending time in libraries and archives, fieldwork and interviews, running experiments, analysing data, problem-solving, creative thinking, writing and communicating your findings to others. It’s just as important to ask yourself which parts of it don’t appeal and consider how you would handle those aspects.

Once you’ve done this assessment you can think more about what a PhD might lead to.

Benefits of the PhD experience

The skills you gain and improve during a PhD are transferable and applicable to a wide range of careers. Prospective employers look for those with experience of doing research and a PhD is a research-based degree. What you researched might be directly related to jobs you apply for but it doesn’t need to be: it’s the fact that you have research experience that counts.

Employers also look for those with good written and spoken communication skills (online and face to face) and who can plan and deliver presentations. These could be for team meetings, conferences or sales pitches. Whilst doing a PhD, you will be networking not just within your university but in other areas. In recent years, networking skills have become more important in the work environment. Having networking experience, whether it’s ‘working the room’ at a conference or meeting or attending an online event will boost your potential and help you stand out.

You can develop your networks by attending conferences, talks and other events apart from regular contact with other students and tutors. These may be online given COVID restrictions but opportunities for face- to- face events have increased in the second half of 2021. These contacts can provide useful support and also share work opportunities. There are many online study and research forums  that can help you through your PhD and also offer opportunities for  finding work whilst you are studying  and post-graduation. Some of these online forums may be arranging small-scale physical meet-ups.

Considering Career Possibilities

Whilst a PhD is often seen as professional training for academia, this is just one possibility. In the UK less than half of PhD graduates become academics and this figure can lower in other countries.

As with any career ambitions, assessment of all that is involved. Academics are expected to do much more than research, teach and supervise students.

If this is what you’re aiming for, start preparing by taking up opportunities for  part-time teaching  that might fit into your schedule. This is valuable work experience even if you later decide not to go into academia.

Outside Academia

There are many options in the professions, business and management, public sector and more. From small and local, to large and global, many companies and institutions seek highly qualified personnel. Think about the  types of organisations  you could work for: everything from large multinationals, NGOs, charities, local and national government, regulatory bodies and agencies, SMEs (small to medium enterprises with under 250 employees). The vast majority of companies in the UK are SMEs and offer excellent career progression opportunities.

Different employment sectors have their specific features but increasingly overlap as economic, technological and political changes come into play. Whilst we can distinguish the public and private sectors these have shown degrees of convergence in recent years.

The Professions

These typically involve prolonged training and formal qualifications such as accountancy, civil service, law and medicine. Having a PhD is considered to be  indicative of professional development  but additional training may be required for your chosen area.

Self-employment

This category encompasses all forms of working for yourself, whether setting up a small business by yourself or with others, doing consultancy work or a mix of these.

The self-employed account for around 15% of the labour force in the UK.

There are possibilities of freelance working within academia as well as in other areas, by packaging and selling your expertise and skills. The advantages include being ‘your own boss’, taking on work you choose and being free of the 9 to 5 routine.

There are also challenges, with responsibilities for legal compliance and taxation. There may be long working hours without the ‘cushion’ of secure monthly income and paid holidays.

In the past decade, digital entrepreneurship has rapidly expanded with new start-ups coming online all the time. This trend has increased over the past 18 months as more people lost jobs and decided to set up their own businesses from home.

It’s likely that the gig economy will continue to develop and you may consider if you want to enter this as a sole proprietor or as an employee if self-employment is not your preferred career route.

Not-For-Profit

This includes charities, NGOs and community interest companies. As in other sectors, some are small and local whilst others are global, eg. Oxfam. NGOs might focus on one area or multiple parts of the world but a specific theme such as human rights or the environment. There are openings at different levels and whilst they may rely on volunteers they do have paid positions in fund-raising, advocacy, administration, marketing and management.

The skills and experience gained by a PhD graduate can certainly be applied elsewhere, particularly if you keep an open mind and your eyes on the jobs market from the early days of your  doctoral journey . You can upgrade your employability profile by networking and taking advantage of your university’s employability support and opportunities including gaining some work experience. This is always a big bonus and increasingly required by employers.

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Dr. Ruth Cherrington

Ruth Cherrington has a long record as a higher education professional. She has been a lecturer, trainer and employability adviser both in the UK and abroad. Ruth has always been committed to maximizing the professional development of those she works with. Another strand to her career is as a writer, with a wide range of publications to her name. Ruth enjoys travelling to meet former students and colleagues across the world. LinkedIn

https://www.linkedin.com/in/ruthcherringtonnumber7/

Reader Interactions

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12th March 2021 at 11:16 pm

I am an environmental chemist working in the waste management industry. I have an MSci degree, and hope to stay in this industry. I am curious if pursuing a PhD will improve my job prospects later down the line, or would working towards a chartership be more valuable?

3rd February 2023 at 2:47 pm

Pursuing a Ph.D. doesn’t only polish your skills, But also gives you a new form of understanding the demand for knowledgeable people required by industries. If you look outside towards different companies offering you more money and benefits, Ph.D. works as fuel to reach higher posts. In the education sector, there is a demand for Ph.D. professors. If you have an industry experience with a Ph.D. your hourly wage varies from around £70 to £100 an hour. I wish you best of luck

16th June 2024 at 9:28 pm

I am already 46 and eager to pursue my PHD. Am I too old to start it?

10th July 2024 at 7:14 am

I’m 41 years having 15 years of experience in IT and bssed out in India.Im really interested to do PhD in either cybersecurity with AI or with some interesting topic with AI.As an organization, management is insisting all employees to use AI as a tool but I wanted to investigate more on it .. Please Advice…

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Online PhD in Clinical Research: Scope and Job Opportunities 

Blog Summary 

Introduction .

Embarking on a journey toward an online PhD in Clinical Research opens doors to possibilities. Clinical Research, the systematic investigation of treatments and therapies, is pivotal in advancing healthcare. Pursuing a PhD in this field signifies a commitment to deepening understanding and contributing to medical progress. The convenience and flexibility of online education make it an ideal avenue for aspiring researchers, allowing them to balance academic pursuits with other commitments. 

Moreover, online platforms offer specialized courses tailored to the nuances of Clinical Research, providing students with comprehensive knowledge and practical skills. In this digital age, harnessing the power of online learning is vital to unlocking the vast potential of Clinical Research studies. 

Exploring Online PhD in Clinical Research 

In today’s fast-paced world, pursuing higher education has become more accessible than ever, thanks to the advent of online learning platforms. An Online PhD in Clinical Research program allows students to increase their understanding and expertise in this vital field from the comfort of their homes. 

What is an Online PhD in Clinical Research? 

An online PhD in Clinical Research is a doctoral program designed to equip students with the abilities and information to do independent Research in clinical settings. It delves deep into the methodologies, ethical considerations, and data analysis techniques relevant to clinical Research.

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How the PhD Program Works

Program Overview

Completing your doctorate at Wharton requires 5 years of full-time study. The first 2 years in the program prepare you for admission to candidacy by taking courses, qualifying exams, and starting research projects. In the last few years, you are primarily conducting research full-time including writing and defending your doctoral dissertation.

Admission to candidacy.

You begin by taking courses required for your program of study. All programs requires a preliminary exam, which may be either oral or written.

Some programs may have further requirements, such as an additional exam or research paper. If you enter with a master’s degree or other transfer credit, you may satisfy the formal course requirements more quickly.

Beginning the Wharton PhD Curriculum How the first two years of the Wharton program helped students discover their interests, learn the tools of the profession, and fuel their passion for teaching.

The Doctoral Dissertation

Upon successful completion of coursework and passing a preliminary examination, you are admitted to candidacy for the dissertation phase of your studies.

Your doctoral dissertation should contain original research that meets standards for published scholarship in your field. You are expected to be an expert in the topic you choose to research.

You are admitted to candidacy for the dissertation phase of your studies upon successful completion of coursework and passing a preliminary examination, but you can start thinking about and working on research of relevance at any time.

The dissertation process culminates with a “defense,” in which you defend the proposal orally before your dissertation committee.

While working on your dissertation, you interact extensively with Wharton faculty. Together with interested faculty, you create your own research community that includes your dissertation advisor and dissertation committee.

Policies and Procedures

Get more detailed explanation of course requirements, academic standards, the Teacher Development Program, time limits, and dissertation procedures and requirements.

Sample Program Sequence

Years 1 & 2.

Coursework Examination Research Papers Research Activities Field-Specific Requirements

Directed Reading & Research Admission to Candidacy Formulation of Research Topic

Years 4 & 5

Continued Research Oral Examination Dissertation

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How wharton makes it easy to be successful, closing the tenure gap for business faculty of color.

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Teaching Research Skills That Transfer to Future Projects

Exploratory research teaches skills that have lifelong use..

Updated August 1, 2024 | Reviewed by Monica Vilhauer

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This post is the fourth in a series.

When helping students become researchers, the goal is not only to equip students to tackle a current research project but also to ensure the learned skills will stay with them for future endeavors. Students must understand which research staples must be applied under any circumstances (like critically evaluating sources or following ethical guidelines) while maintaining the flexibility to try different approaches and make new connections. Students at Laguna Beach High School (LBHS) are learning to do just that.

In Part I of this series I spoke to Jun Shen, the passionate teacher and ed-tech coordinator who runs LBHS’s Authentic Exploratory Research (AER) program . AER is an independent research course inspired by Palo Alto Unified School District’s Advanced Authentic Research program . The program pairs students with adult mentors (such as LBUSD staff, industry experts, and academics) who assist the teens in researching their big questions in fields of their choice.

Former LBHS student Carter Ghere was the third teenager to give us an account of his experience in AER and the findings that his AER research produced. A benefit to meeting with Ghere was that he has since moved on to projects outside the AER program, such as promoting physical and mental health . The research skills Ghere honed in AER, combined with his passion for his new endeavors, show us how students can learn research skills in a way that has lasting benefits.

Jenny Grant Rankin: What can teachers do to help students research effectively, not only for current projects but also for future research endeavors?

Carter Ghere: Teachers can encourage students to think about minor aspects of the project that greatly influence the thesis rather than just the thesis question itself. When I researched car design and why it varies, I had to consider each factor that could help me build a strong argument. What started as research on cars very quickly turned into research into socioeconomics, societal upbringing, and government involvement in diplomatic events and conflict. Automotive design changed because manufacturers were competing against each other to sell more cars or improve efficiency, but mass appeal is the biggest driving aspect of change, so I had to research what changes mass appeal and where interests originate from. Laterally, researching aspects of influence opens up much research to apply to your projects, instead of searching for the answer most people already know. Teachers can teach their students how to see the hidden influences, draw conclusions themselves to strengthen their arguments, and accelerate the research process. Knowing how to do research effectively carries over a lifetime, making every new learning endeavor exciting for students instead of monotonous.

JGR: What was the most significant thing you learned about conducting research?

CG: Relevance and impact. The biggest thing I learned while I was conducting research was keeping in mind how your study affects the current information already available. It’s easy to research and quote what most people know, but genuinely effective research isn’t commonly known or even thought of; the research is supposed to question the current knowledge to create new knowledge.

JGR: What was the most significant thing you learned about communicating research or other work?

CG: Knowing your audience is the biggest thing I learned about communicating my work. Putting myself in the shoes of someone reading my work helped me curate my research to better explain my findings to someone who may need to learn about my topic or why this is important. The last thing you want your audience to feel is confusion; a clear, simple explanation of your findings helps the reader draw their connections and relate them to what they already know.

JGR: What lessons learned in AER do you find yourself applying in your current efforts to promote mental health?

CG: The research experience I have from AER accelerated the work I’ve done beyond high school. In terms of research and the actual information I give out, I know that what I’m discovering isn’t new, but the personal opinion that I have is, and that’s what AER taught me. The thoughts that I have on the subject matter of lifestyle and self-development have more relevance than just plain information.

Learning through apprenticeship and embracing the guidance of a mentor profoundly expanded my understanding. This experience made me realize the vast opportunities I still have to learn and grow. At AER, I had the chance to engage in research, connect with experts in the field, develop personal convictions that I am passionate about, ensure these ideas resonate with others, and communicate them effectively.

Ghere demonstrates what we want students to be able to do with the knowledge and skills we teach: to remember, apply, and develop them perpetually. Ideally, as in Ghere’s case, students also use their research skills to help others and improve our world. To continue reading, look for Part V .

Jenny Grant Rankin, Ph.D., is a Fulbright Specialist for the U.S. Department of State.

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• 06 August 2024

Our local research project put us on the global stage — here’s how you can do it, too

• Seyoon Lee 0 ,
• Hanjae Lee 1 ,
• Juhyun Kim 2 &
• Jong-Il Kim 3

Seyoon Lee is a PhD candidate at the Genomic Medicine Institute, Medical Research Center, Seoul National University, and in the Department of Biomedical Sciences, Seoul National University Graduate School, Seoul, South Korea.

You can also search for this author in PubMed   Google Scholar

Hanjae Lee is a PhD candidate at the Genomic Medicine Institute, Department of Translational Medicine, and in the Department of Dermatology, Seoul National University College of Medicine, Seoul, South Korea.

Juhyun Kim is a PhD candidate at the Genomic Medicine Institute and in the Department of Biomedical Sciences, Seoul National University Graduate School, Seoul, South Korea.

Jong-Il Kim is director of the Genomic Medicine Institute, chair of the Department of Biomedical Sciences, Seoul National University Graduate School, Seoul, South Korea, and head principal investigator of the SCAID project.

You have full access to this article via your institution.

People travel from across South Korea to receive medical treatment in Seoul. Credit: Will & Deni McIntyre/Getty

Later this year, South Korea is expected to sign up to the European Union’s research-funding programme, Horizon Europe . It’s a good time to reflect on the nature of large collaborative projects — and, in particular, when cross-border collaboration is most beneficial and when a deeper dive into local issues can be more rewarding.

Large international collaborations have unquestionably produced great breakthroughs. Sequencing the human genome , for example, took 13 years of work by 20 institutions in 6 countries 1 . But large consortia such as these are almost always established in the same few countries: the United States, the United Kingdom and others in Europe. For scientists working elsewhere, setting up a large international project can seem unachievable, given the billion-dollar price tags and the networks of contacts required.

And, sometimes, it is not the best solution. Global projects spearheaded in a few countries can have biases — for example, people of Asian descent are often under-represented in international genetic studies initiated in the West. National laws on acquiring data can differ, meaning that researchers need to conduct experiments differently in different regions, introducing biases. And the logistical complexity of coordinating a project across multiple countries in different time zones and with different work cultures can be problematic when rapid data collection and analysis are crucial 2 .

There is an alternative — set up a large local consortium in one nation.

Cancer research needs a better map

We’ve done just that in Seoul. Our single-cell atlas of immune diseases (SCAID) consortium is a multi-institutional effort led by one of us (J.-I.K.), alongside 23 others. Running since April 2022, the project now involves 120 South Korean clinicians, immunologists, geneticists and bioinformaticians (including S.L., H.L. and J.K., who work in J.-I.K’s group).

We aim to map gene expression in millions of individual cells from people who have immune-related diseases , including (but not limited to) rheumatoid arthritis, inflammatory bowel disease, interstitial lung disease and alopecia areata. Systemic immune diseases are thought to affect at least 1 in 20 people 3 . They are often incurable and cause debilitating symptoms, from chronic skin rashes to skeletomuscular changes. They can be fatal if they are not managed appropriately. We hope that our research will reveal similarities between 16 diverse diseases that manifest across the body, and help to uncover ways to use treatments more effectively.

Our experiences have shown us that a regional consortium can be an efficient way to ask crucial research questions. Here, we share two broad lessons that we hope will help others to build effective regional consortia.

Find a niche

To compete in international circles, local consortia need to focus on addressing research questions that they are in a unique position to answer. This might be because of the particular mix of expertise of local researchers. It might be the regulatory environment in a country. Or it might be specific to the geography of the place where the research is done.

In our case, we were inspired to set up SCAID by an international consortium called the Human Cell Atlas (HCA) . Since 2016, it has been trying to map every single cell type in the human body using state-of-the art genomic technology. The next logical step is to create similar atlases for diseased cells. But this involves bringing in specialized clinicians for each disease and obtaining proper consent from a large number of people.

This can be hard to achieve in a global consortium, in which each country has distinct legislative frameworks, ethics committees and medical systems 4 . For instance, the International HapMap Project — a genome-sequencing project launched in 2002 with researchers from six countries — needed to spend months in community consultation in Nigeria before it was able to obtain ethics approvals 5 . It also faced concerns raised by community advisory groups in Japan and China around depositing biological samples in overseas repositories. Overcoming these obstacles took 18 months 6 .

For these reasons, most single-cell studies of disease data sets have focused on single diseases in single tissues, for simplicity. By contrast, restricting our study to a single country with one legislative framework has made it easier for us to gain ethics and individual approval, allowing us to study multiple diseases across multiple tissues.

Seoul National University Hospital is one of 56 general hospitals in the South Korean capital. Credit: Anthony Wallace/AFP via Getty

Seoul also has other benefits for such a project. First, it’s easy to enlist a diverse range of participants in the city. South Korea has a universal medical-insurance system that is mandatory for all residents 7 . This avoids biases that can arise when participants are part of a private health-insurance system. And people from across the country and all socio-economic classes travel to Seoul for treatment — the city’s cluster of 56 general hospitals can be reached from anywhere in South Korea in half a day.

The concentration of hospitals also makes it easy to transfer samples quickly from donors to our central laboratory for analysis — it is no more than two hours’ drive from any hospital. Such proximity is a great advantage in single-cell genomics, because RNA — which is analysed to ascertain gene expression — degrades within hours once a sample is collected. A US National Institutes of Health large-scale genetics project called the Genotype–Tissue Expression project, for instance, found variability in the quality of RNA in its samples, depending on the time between collection and processing. This variability could skew interpretations of gene-expression data, and the researchers had to develop ways to account for it in their analyses 8 .

Having a centralized hub prevents the problem of batch effects — undesired differences between samples — that can arise if samples are processed or analysed differently by different centres 9 , 10 . Handling batch effects is a big task for international consortia. The HCA, for instance, has a dedicated team of researchers to check for and minimize such effects 11 .

Exploiting this niche is already proving fruitful for us. So far, we’ve collected more than 500 samples from 334 donors. We have analysed more than two million cells — equivalent to the second-largest data set collected in the HCA project so far. Our early analysis hints at common features between diseases: although symptoms arise in different organs, we are identifying distinct immune profiles that group the diseases into a few major categories.

Unblock research bottlenecks with non-profit start-ups

Still, being small and nimble comes with challenges. Local consortia need to be aware that they might lack some expertise , and they need to be prepared to seek help. Our consortium faced obstacles in obtaining ethics approvals, because each hospital review board had different requirements and concerns. Getting approval from each board was arduous, and required persistence when asking for opinions of the boards themselves, along with those of the Korea National Institute for Bioethics Policy and Korean Bioinformation Center. Nonetheless, it was easier than grappling with multiple international rules around ethics and data collection.

To make this process smoother for others, it would help for institutions in a country to standardize their ethical-review processes and data-sharing agreements, ensuring that both comply with national regulations. Furthermore, institutions should establish collaborative networks to share best practices and discuss common challenges. These steps could ease the administrative burden on local consortia considerably, and accelerate their progress.

Not all countries will have the strong technical skills of the South Korean workforce, nor the established biobanking repositories for genetic and clinical data, which are essential in projects such as ours. For scientists in countries without this infrastructure, international consortia can be a valuable source of guidance. For instance, the HCA’s Equity Working Group specifically aims to engage diverse geographical and ethnic groups in its projects 12 . By participating in such initiatives, countries can gain access to expertise, resources and best practices, helping them to overcome technical challenges and build their capabilities.

Build in local benefits

Regional projects should reflect the needs of the local community, both for ethical reasons and to attract funding. Funders are more likely to invest in big projects that can benefit citizens. Researchers must make those benefits clear.

This might mean championing a field to governments and other funders. In South Korea, most research funding comes from the government — scientists propose broad topics that need funding, and the government selects those that align with its own goals and puts out funding calls, for which all researchers can apply. So genomicists, immunologists and bioinformaticians — not all of whom are members of the SCAID consortium — requested that the South Korean government fund a large-scale disease single-cell atlas. These scientists spelled out how the data could ultimately help researchers and clinicians to improve understanding of the disease predispositions that are unique to South Koreans. This will hopefully speed up the development of precision medicines tailored to the country’s own population.

South Korean scientists’ outcry over planned R&D budget cuts

In countries that do not have official channels for petitioning the government, raising the profile of a field might involve using networks of contacts to meet with funders, or publishing papers that outline a field’s potential. Persistence is key — scientists must keep voicing their needs and perspectives.

Researchers must also give careful thought to how their project will benefit local science. SCAID was designed to maximize the long-term benefits for the South Korean researchers and clinicians involved.

To develop researchers’ careers, we hold regular seminars and workshops focused on learning skills and network building. Cross-disciplinary collaborations are one focus. For example, bioinformaticians are working with clinicians on a strategy pinpointing the specialized data that should be collected for each disease — such as acquiring information on immune receptors for specific disorders. Bioinformaticians are also exploiting the expertise of clinicians to help interpret their analyses. This includes the identification of abnormal cell states, which can be hard to distinguish from artefacts in the data without a deep knowledge of disease. These networks of contacts will be useful for many projects long after SCAID is completed.

Once established, local consortia need not exist in isolation. They can complement existing global projects by adding diverse data, and can act as stepping stones for future global consortia. For instance, many scientists have approached us, intrigued by the scale and potential of our work, and enquired about possible collaborations.

We are keen for other regional groups to generate international databases from separate efforts led by those who understand their own local needs and niches best. We encourage them to start by seeking funding for a consortium to address the needs of their fellow citizens, and to eventually pool their knowledge.

Whatever the field, if a consortium is run well, it can cultivate a dynamic cluster of competent researchers, laying the groundwork for international recognition and collaboration.

Nature 632 , 256-258 (2024)

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