Healthcare: Colon Cancer Essay
Introduction, causes of colon cancer, reducing the risk of colon cancer, reference list.
The colon refers to the longest section of the large gut and the most low-down section of the digestive arrangement in the human body. Within this part, water and salt are drawn out from solid desecrate ahead of it proceeding through the terminal section of the alimentary canal and leaving the body by way of the anus.
Cancer is a group of disorders typified by uncontrollable cell development, and colon cancer comes about when this uninhibited cell development kicks off with cells in the large intestine. For the most part, colon cancer disorder(s) begin to form small, nonmalignant growths referred to as adenomatous polyps that appear on the interior walls of the large tract (U.S. Preventive Services Task Force, March 2007, p. 361). A number of these cysts may develop into dangerous colon cancers with time if they are not gotten rid of during a procedure of endoscopy. Colon cancer cells will attack and harm hale and hearty tissue that is adjacent to the growth resulting in quite a several difficulties.
Following the formation of cancerous growths, the malignant cells may move by way of blood and lymph systems, extending to other sections of the body. These cancerous cells can develop in quite a several places, attacking and devastating other fit tissues in the body. This process is referred to as metastasis, and the outcome is a more severe situation that is very hard to take care of. Statistics show that in the United States close to 112,000 persons are identified to be having this disorder every year.
The warning signs of this disorder are pretty diverse and are contingent upon where the cancer is situated, where it has extended, and the size of the growth. It is widespread for those with the infection to have no signs in the initial periods of the disorder. Nonetheless, when the disorder develops, some signs manifest themselves. They mostly commence with diarrhea or constipation. These are followed by other symptoms which include, alterations in feces regularity, blood in feces, aches in the process of bowel movement(s), frequent urges to poop, inexplicable loss of weight, among others.
In cases where the disorder has extended to other parts of the body, further signs can occur in the affected sections. Such warning signs will rely on the area to which the disorder has spread, with the liver being the most frequent.
There are quite a several causes of this disorder and among them there features nutrition, obesity, and fitness of an individual. The types of foods that one majorly consumes determine whether they are at risk or not of developing this disorder (Su LJ, Arab L, 2004, p. 111). Research has established that diets containing high levels of fat and cholesterol, particularly from animals, put consumers at high risk of developing the disorder.
Obesity refers to a state in which a person surpasses their advocated weight. It is a step clear of being overweight, and it is a well-known cause of colon cancer. Studies have revealed that inactive lifestyles as well lead to the development of colon cancer.
The best place to begin is ensuring that one consumes the right foods. Foods rich in fiber are advocated, as well as fresh fruits, vegetables, and white meat. Red meat should be kept to a minimum (U.S. Preventive Services Task Force, March 2007, p. 364).
Alongside a healthy diet, people need to ensure that they exercise their bodies appropriately. All body systems work effectively through this and it also keeps complications like obesity at bay. Alcohol intake and smoking need to be kept to a minimum or even avoided as well.
Su LJ, Arab L (2004). Alcohol consumption and risk of colon cancer: evidence from the national health and nutrition examination survey I epidemiologic follow-up study. Nutr Cancer 50 (2): 111–9.
U.S. Preventive Services Task Force (2007). Routine aspirin or nonsteroidal anti- inflammatory drugs for the primary prevention of colorectal cancer: U.S. Preventive Services Task Force recommendation statement. Ann. Intern. Med. 146 (5): 361–4.
- Health Behaviors That Impact Risk Factors for Diseases
- The Pap Smear Screening Procedure
- Pathology for Adenocarcinoma of the Colon
- Genetic Testing: Screening for Colon Cancer
- Cancer and Tumor Suppressor Genes
- Dosage & Regimen for MEK Inhibitor: Cancer Clinical Trial
- Breast Cancer Susceptibility Gene (BRCA2)
- Prostate Cancer Pathophysiology and Management
- Esophageal Cancer Overview and Analysis
- Ovarian Cancer Overview and Analysis
- Chicago (A-D)
- Chicago (N-B)
IvyPanda. (2022, March 29). Healthcare: Colon Cancer. https://ivypanda.com/essays/healthcare-colon-cancer/
"Healthcare: Colon Cancer." IvyPanda , 29 Mar. 2022, ivypanda.com/essays/healthcare-colon-cancer/.
IvyPanda . (2022) 'Healthcare: Colon Cancer'. 29 March.
IvyPanda . 2022. "Healthcare: Colon Cancer." March 29, 2022. https://ivypanda.com/essays/healthcare-colon-cancer/.
1. IvyPanda . "Healthcare: Colon Cancer." March 29, 2022. https://ivypanda.com/essays/healthcare-colon-cancer/.
Bibliography
IvyPanda . "Healthcare: Colon Cancer." March 29, 2022. https://ivypanda.com/essays/healthcare-colon-cancer/.
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Theses & Dissertations: Cancer Research
Theses/dissertations from 2024 2024.
Novel Spirocyclic Dimer (SpiD3) Displays Potent Preclinical Effects in Hematological Malignancies , Alexandria Eiken
Chemotherapy-Induced Modulation of Tumor Antigen Presentation , Alaina C. Larson
Understanding the role of MASTL in colon homeostasis and colitis-associated cancer development , Kristina Pravoverov
Dying Right: Supporting Anti-Cancer Therapy Through Immunogenic Cell Death , Elizabeth Schmitz
Therapeutic Effects of BET Protein Inhibition in B-cell Malignancies and Beyond , Audrey L. Smith
Targeting KSR1 to inhibit stemness and therapy resistance , Heidi M. Vieira
Identifying the Molecular Determinants of Lung Metastatic Adaptation in Prostate Cancer , Grace M. Waldron
Identification of Mitotic Phosphatases and Cyclin K as Novel Molecular Targets in Pancreatic Cancer , Yi Xiao
Theses/Dissertations from 2023 2023
Development of Combination Therapy Strategies to Treat Cancer Using Dihydroorotate Dehydrogenase Inhibitors , Nicholas Mullen
Overcoming Resistance Mechanisms to CDK4/6 Inhibitor Treatment Using CDK6-Selective PROTAC , Sarah Truong
Theses/Dissertations from 2022 2022
Omics Analysis in Cancer and Development , Emalie J. Clement
Investigating the Role of Splenic Macrophages in Pancreatic Cancer , Daisy V. Gonzalez
Polymeric Chloroquine in Metastatic Pancreatic Cancer Therapy , Rubayat Islam Khan
Evaluating Targets and Therapeutics for the Treatment of Pancreatic Cancer , Shelby M. Knoche
Characterization of 1,1-Diarylethylene FOXM1 Inhibitors Against High-Grade Serous Ovarian Carcinoma Cells , Cassie Liu
Novel Mechanisms of Protein Kinase C α Regulation and Function , Xinyue Li
SOX2 Dosage Governs Tumor Cell Identity and Proliferation , Ethan P. Metz
Post-Transcriptional Control of the Epithelial-to-Mesenchymal Transition (EMT) in Ras-Driven Colorectal Cancers , Chaitra Rao
Use of Machine Learning Algorithms and Highly Multiplexed Immunohistochemistry to Perform In-Depth Characterization of Primary Pancreatic Tumors and Metastatic Sites , Krysten Vance
Characterization of Metastatic Cutaneous Squamous Cell Carcinoma in the Immunosuppressed Patient , Megan E. Wackel
Visceral adipose tissue remodeling in pancreatic ductal adenocarcinoma cachexia: the role of activin A signaling , Pauline Xu
Phos-Tag-Based Screens Identify Novel Therapeutic Targets in Ovarian Cancer and Pancreatic Cancer , Renya Zeng
Theses/Dissertations from 2021 2021
Functional Characterization of Cancer-Associated DNA Polymerase ε Variants , Stephanie R. Barbari
Pancreatic Cancer: Novel Therapy, Research Tools, and Educational Outreach , Ayrianne J. Crawford
Apixaban to Prevent Thrombosis in Adult Patients Treated With Asparaginase , Krishna Gundabolu
Molecular Investigation into the Biologic and Prognostic Elements of Peripheral T-cell Lymphoma with Regulators of Tumor Microenvironment Signaling Explored in Model Systems , Tyler Herek
Utilizing Proteolysis-Targeting Chimeras to Target the Transcriptional Cyclin-Dependent Kinases 9 and 12 , Hannah King
Insights into Cutaneous Squamous Cell Carcinoma Pathogenesis and Metastasis Using a Bedside-to-Bench Approach , Marissa Lobl
Development of a MUC16-Targeted Near-Infrared Antibody Probe for Fluorescence-Guided Surgery of Pancreatic Cancer , Madeline T. Olson
FGFR4 glycosylation and processing in cholangiocarcinoma promote cancer signaling , Andrew J. Phillips
Theses/Dissertations from 2020 2020
Cooperativity of CCNE1 and FOXM1 in High-Grade Serous Ovarian Cancer , Lucy Elge
Characterizing the critical role of metabolic and redox homeostasis in colorectal cancer , Danielle Frodyma
Genomic and Transcriptomic Alterations in Metabolic Regulators and Implications for Anti-tumoral Immune Response , Ryan J. King
Dimers of Isatin Derived Spirocyclic NF-κB Inhibitor Exhibit Potent Anticancer Activity by Inducing UPR Mediated Apoptosis , Smit Kour
From Development to Therapy: A Panoramic Approach to Further Our Understanding of Cancer , Brittany Poelaert
The Cellular Origin and Molecular Drivers of Claudin-Low Mammary Cancer , Patrick D. Raedler
Mitochondrial Metabolism as a Therapeutic Target for Pancreatic Cancer , Simon Shin
Development of Fluorescent Hyaluronic Acid Nanoparticles for Intraoperative Tumor Detection , Nicholas E. Wojtynek
Theses/Dissertations from 2019 2019
The role of E3 ubiquitin ligase FBXO9 in normal and malignant hematopoiesis , R. Willow Hynes-Smith
BRCA1 & CTDP1 BRCT Domainomics in the DNA Damage Response , Kimiko L. Krieger
Targeted Inhibition of Histone Deacetyltransferases for Pancreatic Cancer Therapy , Richard Laschanzky
Human Leukocyte Antigen (HLA) Class I Molecule Components and Amyloid Precursor-Like Protein 2 (APLP2): Roles in Pancreatic Cancer Cell Migration , Bailee Sliker
Theses/Dissertations from 2018 2018
FOXM1 Expression and Contribution to Genomic Instability and Chemoresistance in High-Grade Serous Ovarian Cancer , Carter J. Barger
Overcoming TCF4-Driven BCR Signaling in Diffuse Large B-Cell Lymphoma , Keenan Hartert
Functional Role of Protein Kinase C Alpha in Endometrial Carcinogenesis , Alice Hsu
Functional Signature Ontology-Based Identification and Validation of Novel Therapeutic Targets and Natural Products for the Treatment of Cancer , Beth Neilsen
Elucidating the Roles of Lunatic Fringe in Pancreatic Ductal Adenocarcinoma , Prathamesh Patil
Theses/Dissertations from 2017 2017
Metabolic Reprogramming of Pancreatic Ductal Adenocarcinoma Cells in Response to Chronic Low pH Stress , Jaime Abrego
Understanding the Relationship between TGF-Beta and IGF-1R Signaling in Colorectal Cancer , Katie L. Bailey
The Role of EHD2 in Triple-Negative Breast Cancer Tumorigenesis and Progression , Timothy A. Bielecki
Perturbing anti-apoptotic proteins to develop novel cancer therapies , Jacob Contreras
Role of Ezrin in Colorectal Cancer Cell Survival Regulation , Premila Leiphrakpam
Evaluation of Aminopyrazole Analogs as Cyclin-Dependent Kinase Inhibitors for Colorectal Cancer Therapy , Caroline Robb
Identifying the Role of Janus Kinase 1 in Mammary Gland Development and Breast Cancer , Barbara Swenson
DNMT3A Haploinsufficiency Provokes Hematologic Malignancy of B-Lymphoid, T-Lymphoid, and Myeloid Lineage in Mice , Garland Michael Upchurch
Theses/Dissertations from 2016 2016
EHD1 As a Positive Regulator of Macrophage Colony-Stimulating Factor-1 Receptor , Luke R. Cypher
Inflammation- and Cancer-Associated Neurolymphatic Remodeling and Cachexia in Pancreatic Ductal Adenocarcinoma , Darci M. Fink
Role of CBL-family Ubiquitin Ligases as Critical Negative Regulators of T Cell Activation and Functions , Benjamin Goetz
Exploration into the Functional Impact of MUC1 on the Formation and Regulation of Transcriptional Complexes Containing AP-1 and p53 , Ryan L. Hanson
DNA Polymerase Zeta-Dependent Mutagenesis: Molecular Specificity, Extent of Error-Prone Synthesis, and the Role of dNTP Pools , Olga V. Kochenova
Defining the Role of Phosphorylation and Dephosphorylation in the Regulation of Gap Junction Proteins , Hanjun Li
Molecular Mechanisms Regulating MYC and PGC1β Expression in Colon Cancer , Jamie L. McCall
Pancreatic Cancer Invasion of the Lymphatic Vasculature and Contributions of the Tumor Microenvironment: Roles for E-selectin and CXCR4 , Maria M. Steele
Altered Levels of SOX2, and Its Associated Protein Musashi2, Disrupt Critical Cell Functions in Cancer and Embryonic Stem Cells , Erin L. Wuebben
Theses/Dissertations from 2015 2015
Characterization and target identification of non-toxic IKKβ inhibitors for anticancer therapy , Elizabeth Blowers
Effectors of Ras and KSR1 dependent colon tumorigenesis , Binita Das
Characterization of cancer-associated DNA polymerase delta variants , Tony M. Mertz
A Role for EHD Family Endocytic Regulators in Endothelial Biology , Alexandra E. J. Moffitt
Biochemical pathways regulating mammary epithelial cell homeostasis and differentiation , Chandrani Mukhopadhyay
EPACs: epigenetic regulators that affect cell survival in cancer. , Catherine Murari
Role of the C-terminus of the Catalytic Subunit of Translesion Synthesis Polymerase ζ (Zeta) in UV-induced Mutagensis , Hollie M. Siebler
LGR5 Activates TGFbeta Signaling and Suppresses Metastasis in Colon Cancer , Xiaolin Zhou
LGR5 Activates TGFβ Signaling and Suppresses Metastasis in Colon Cancer , Xiaolin Zhou
Theses/Dissertations from 2014 2014
Genetic dissection of the role of CBL-family ubiquitin ligases and their associated adapters in epidermal growth factor receptor endocytosis , Gulzar Ahmad
Strategies for the identification of chemical probes to study signaling pathways , Jamie Leigh Arnst
Defining the mechanism of signaling through the C-terminus of MUC1 , Roger B. Brown
Targeting telomerase in human pancreatic cancer cells , Katrina Burchett
The identification of KSR1-like molecules in ras-addicted colorectal cancer cells , Drew Gehring
Mechanisms of regulation of AID APOBEC deaminases activity and protection of the genome from promiscuous deamination , Artem Georgievich Lada
Characterization of the DNA-biding properties of human telomeric proteins , Amanda Lakamp-Hawley
Studies on MUC1, p120-catenin, Kaiso: coordinate role of mucins, cell adhesion molecules and cell cycle players in pancreatic cancer , Xiang Liu
Epac interaction with the TGFbeta PKA pathway to regulate cell survival in colon cancer , Meghan Lynn Mendick
Theses/Dissertations from 2013 2013
Deconvolution of the phosphorylation patterns of replication protein A by the DNA damage response to breaks , Kerry D. Brader
Modeling malignant breast cancer occurrence and survival in black and white women , Michael Gleason
The role of dna methyltransferases in myc-induced lymphomagenesis , Ryan A. Hlady
Design and development of inhibitors of CBL (TKB)-protein interactions , Eric A. Kumar
Pancreatic cancer-associated miRNAs : expression, regulation and function , Ashley M. Mohr
Mechanistic studies of mitochondrial outer membrane permeabilization (MOMP) , Xiaming Pang
Novel roles for JAK2/STAT5 signaling in mammary gland development, cancer, and immune dysregulation , Jeffrey Wayne Schmidt
Optimization of therapeutics against lethal pancreatic cancer , Joshua J. Souchek
Theses/Dissertations from 2012 2012
Immune-based novel diagnostic mechanisms for pancreatic cancer , Michael J. Baine
Sox2 associated proteins are essential for cell fate , Jesse Lee Cox
KSR2 regulates cellular proliferation, transformation, and metabolism , Mario R. Fernandez
Discovery of a novel signaling cross-talk between TPX2 and the aurora kinases during mitosis , Jyoti Iyer
Regulation of metabolism by KSR proteins , Paula Jean Klutho
The role of ERK 1/2 signaling in the dna damage-induced G2 , Ryan Kolb
Regulation of the Bcl-2 family network during apoptosis induced by different stimuli , Hernando Lopez
Studies on the role of cullin3 in mitosis , Saili Moghe
Characteristics of amyloid precursor-like protein 2 (APLP2) in pancreatic cancer and Ewing's sarcoma , Haley Louise Capek Peters
Structural and biophysical analysis of a human inosine triphosphate pyrophosphatase polymorphism , Peter David Simone
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